BDBM50142614 CHEMBL3758336

SMILES N[C@@H](Cc1cc(Cl)c(Cl)c(c1)-c1cncc(O)c1)C(O)=O

InChI Key InChIKey=JDADEROVQGCQQJ-LBPRGKRZSA-N

Data  7 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142614   

TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi:  2.26E+3nMAssay Description:Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataIC50:  3.70E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair